Downregulation of Lung Toll-Like Receptor 4 Could Effectively Attenuate Liver Transplantation-Induced Pulmonary Damage at the Early Stage of Reperfusion

Acute lung injury (ALI) is a severe complication of orthotopic liver transplantation (OLT) with unclear underline mechanism. Toll-like receptor 4 (TLR4) has been identified as a key receptor mediating inflammation. We hypothesized that TLR4-mediated pulmonary inflammation may contribute to developme...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Chi, Xinjin, Yao, Weifeng, Zhang, Ailan, Ge, Mian, Cai, Jun, Zhou, Shaoli, Xia, Zhengyuan, Luo, Gangjian, Hei, Ziqing
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603309/
https://ncbi.nlm.nih.gov/pubmed/26491225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/383907
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