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Target Therapy of Unresectable or Metastatic Dermatofibrosarcoma Protuberans With Imatinib Mesylate: An Analysis on 22 Chinese Patients

Dermatofibrosarcoma protuberans (DFSP) is a rare, plaque-like tumor of the cutaneous tissue occurring more on the trunk than the extremities and neck. More than 95% of DFSP present anomalies on the 17q22 and 22q13 chromosomal regions leading to the fusion of COL1A1 and PDGFB genes. Surgery is the op...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Wang, Chunmeng, Luo, Zhiguo, Chen, Jie, Zheng, Biqiang, Zhang, Ruming, Chen, Yong, Shi, Yingqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4603059/
https://ncbi.nlm.nih.gov/pubmed/25929918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000000773
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