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Cardiac Protective Effects of Dexrazoxane on Animal Cardiotoxicity Model Induced by Anthracycline Combined With Trastuzumab Is Associated With Upregulation of Calpain-2
Cardiotoxicity is a well-recognized side effect induced by chemotherapeutic drugs such as anthracycline and trastuzumab through different mechanisms. Currently, accumulating evidence supports that dexrazoxane (DZR) can minimize the risk of cardiotoxicity. In this study, we investigated whether dexrz...
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Pubblicato in: | Medicine (Baltimore) |
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Autori principali: | , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Wolters Kluwer Health
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4602968/ https://ncbi.nlm.nih.gov/pubmed/25634181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000000445 |
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