Activation of Vago by interferon regulatory factor (IRF) suggests an interferon system-like antiviral mechanism in shrimp

There is a debate on whether invertebrates possess an antiviral immunity similar to the interferon (IFN) system of vertebrates. The Vago gene from arthropods encodes a viral-activated secreted peptide that restricts virus infection through activating the JAK-STAT pathway and is considered to be a cy...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Li, Chaozheng, Li, Haoyang, Chen, Yixiao, Chen, Yonggui, Wang, Sheng, Weng, Shao-Ping, Xu, Xiaopeng, He, Jianguo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602278/
https://ncbi.nlm.nih.gov/pubmed/26459861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15078
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