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Physiological and pathological roles of tissue plasminogen activator and its inhibitor neuroserpin in the nervous system

Although its roles in the vascular space are most well-known, tissue plasminogen activator (tPA) is widely expressed in the developing and adult nervous system, where its activity is believed to be regulated by neuroserpin, a predominantly brain-specific member of the serpin family of protease inhib...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Lee, Tet Woo, Tsang, Vicky W. K., Birch, Nigel P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602146/
https://ncbi.nlm.nih.gov/pubmed/26528129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00396
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