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APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments
Endocytosis allows cargo to enter a series of specialized endosomal compartments, beginning with early endosomes harboring Rab5 and its effector EEA1. There are, however, additional structures labeled by the Rab5 effector APPL1 whose role in endocytic transport remains unclear. It has been proposed...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4602042/ https://ncbi.nlm.nih.gov/pubmed/26459602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311117 |
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