Different Dynamics for IgG and IgA Memory B Cells in Adolescents following a Meningococcal Serogroup C Tetanus Toxoid Conjugate Booster Vaccination Nine Years after Priming: A Role for Priming Age?

BACKGROUND: Antibody levels wane rapidly after Meningococcal serogroup C conjugate (MenCC) vaccination in young children, rendering the need for an adolescent booster dose. It is not clear whether circulating memory B cells are associated with persistence of MenC-specific antibody levels. METHODS: M...

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Veröffentlicht in:PLoS One
Hauptverfasser: Stoof, Susanne P., Buisman, Anne-Marie, van Rooijen, Debbie M., Boonacker, Rianne, van der Klis, Fiona R. M., Sanders, Elisabeth A. M., Berbers, Guy A. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601787/
https://ncbi.nlm.nih.gov/pubmed/26458006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138665
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