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Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length

Primary cilia start forming within the G1 phase of the cell cycle and continue to grow as cells exit the cell cycle (G0). They start resorbing when cells re-enter the cell cycle (S phase) and are practically invisible in mitosis. The mechanisms by which cilium biogenesis and disassembly are coupled...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Maskey, Dipak, Marlin, Matthew Caleb, Kim, Seokho, Kim, Sehyun, Ong, E-Ching, Li, Guangpu, Tsiokas, Leonidas
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Ltd 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601663/
https://ncbi.nlm.nih.gov/pubmed/26206584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490831
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