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An active site–tail interaction in the structure of hexahistidine-tagged Thermoplasma acidophilum citrate synthase
Citrate synthase (CS) plays a central metabolic role in aerobes and many other organisms. The CS reaction comprises two half-reactions: a Claisen aldol condensation of acetyl-CoA (AcCoA) and oxaloacetate (OAA) that forms citryl-CoA (CitCoA), and CitCoA hydrolysis. Protein conformational changes that...
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| Publicado en: | Acta Crystallogr F Struct Biol Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
International Union of Crystallography
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601594/ https://ncbi.nlm.nih.gov/pubmed/26457521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15015939 |
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