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Structure of DnmZ, a nitrososynthase in the Streptomyces peucetius anthracycline biosynthetic pathway

The anthracyclines are a class of highly effective natural product chemotherapeutics and are used to treat a range of cancers, including leukemia. The toxicity of the anthracyclines has stimulated efforts to further diversify the scaffold of the natural product, which has led to renewed interest in...

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Détails bibliographiques
Publié dans:Acta Crystallogr F Struct Biol Commun
Auteurs principaux: Sartor, Lauren, Ibarra, Charmaine, Al-Mestarihi, Ahmad, Bachmann, Brian O., Vey, Jessica L.
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601581/
https://ncbi.nlm.nih.gov/pubmed/26457508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X15014272
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