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Function of the Mon1-Ccz1 complex on endosomes
Rabs exist in two forms: the inactive GDP- and the active GTP-bound form. GEF proteins mediate the exchange of GDP for GTP and thereby activate Rabs. Although GEFs share a common action, which involves the opening of the Rab nucleotide binding site, they do not contain a conserved catalytic domain....
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| Publicado no: | Small GTPases |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601380/ https://ncbi.nlm.nih.gov/pubmed/25483304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.29040 |
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