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Candida albicans VPS4 contributes differentially to epithelial and mucosal pathogenesis
We have previously demonstrated that the C. albicans pre-vacuolar protein sorting gene VPS4 is required for extracellular secretion of the secreted aspartyl proteases Sap2p and Saps4–6p. Furthermore, the vps4Δ null mutant has been shown to be markedly hypovirulent in a murine tail vein model of diss...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Virulence |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Taylor & Francis
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601185/ https://ncbi.nlm.nih.gov/pubmed/25483774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21505594.2014.956648 |
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