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Candida albicans VPS4 contributes differentially to epithelial and mucosal pathogenesis

We have previously demonstrated that the C. albicans pre-vacuolar protein sorting gene VPS4 is required for extracellular secretion of the secreted aspartyl proteases Sap2p and Saps4–6p. Furthermore, the vps4Δ null mutant has been shown to be markedly hypovirulent in a murine tail vein model of diss...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Rane, Hallie S, Hardison, Sarah, Botelho, Claudia, Bernardo, Stella M, Wormley, Floyd, Lee, Samuel A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601185/
https://ncbi.nlm.nih.gov/pubmed/25483774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21505594.2014.956648
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