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Candida albicans VPS4 contributes differentially to epithelial and mucosal pathogenesis
We have previously demonstrated that the C. albicans pre-vacuolar protein sorting gene VPS4 is required for extracellular secretion of the secreted aspartyl proteases Sap2p and Saps4–6p. Furthermore, the vps4Δ null mutant has been shown to be markedly hypovirulent in a murine tail vein model of diss...
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| Vydáno v: | Virulence |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4601185/ https://ncbi.nlm.nih.gov/pubmed/25483774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21505594.2014.956648 |
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