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Substrate-Initiated Synthesis of Cell-Penetrating Poly(disulfide)s

Lessons from surface-initiated polymerization are applied to grow cell-penetrating poly(disulfide)s directly on substrates of free choice. Reductive depolymerization after cellular uptake should then release the native substrates and minimize toxicity. In the presence of thiolated substrates, propag...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Am Chem Soc
Hauptverfasser: Bang, Eun-Kyoung, Gasparini, Giulio, Molinard, Guillaume, Roux, Aurélien, Sakai, Naomi, Matile, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601153/
https://ncbi.nlm.nih.gov/pubmed/23363440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311961k
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