DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts

BACKGROUND: Studies of DNA damage response are critical for the comprehensive understanding of age-related changes in cells, tissues and organisms. Syrian hamster cells halt proliferation and become presenescent after several passages in standard conditions of cultivation due to what is known as «cu...

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Publicat a:BMC Mol Biol
Autors principals: Solovjeva, Ljudmila, Firsanov, Denis, Vasilishina, Anastasia, Chagin, Vadim, Pleskach, Nadezhda, Kropotov, Andrey, Svetlova, Maria
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601148/
https://ncbi.nlm.nih.gov/pubmed/26458748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-015-0046-4
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