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Synthesis and Evaluation of Novel Erlotinib–NSAID Conjugates as More Comprehensive Anticancer Agents

[Image: see text] A series of novel anticancer agents were designed and synthesized based on coupling of different nonsteroidal anti-inflammatory drugs (NSAIDs) with the epidermal growth-factor receptor (EGFR) tyrosine kinase inhibitor, erlotinib. Both the antiproliferative and pharmacokinetic activ...

詳細記述

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書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Zhang, Yanmei, Tortorella, Micky D., Liao, Jinxi, Qin, Xiaochu, Chen, Tingting, Luo, Jinfeng, Guan, Jiantong, Talley, John J., Tu, Zhengchao
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2015
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601061/
https://ncbi.nlm.nih.gov/pubmed/26487917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00286
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