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Acidic phospholipids govern the enhanced activation of IgG-B cell receptor

B cells that express the isotype-switched IgG-B cell receptor (IgG-BCR) are one of the driving forces for antibody memory. To allow for a rapid memory IgG antibody response, IgG-BCR evolved into a highly effective signalling machine. Here, we report that the positively charged cytoplasmic domain of...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Chen, Xiangjun, Pan, Weiling, Sui, Yinqiang, Li, Hua, Shi, Xiaoshan, Guo, Xingdong, Qi, Hai, Xu, Chenqi, Liu, Wanli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600742/
https://ncbi.nlm.nih.gov/pubmed/26440273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9552
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