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Myosin VI and cardiomyopathy: Left ventricular hypertrophy, fibrosis, and both cardiac and pulmonary vascular endothelial cell defects in the Snell’s waltzer mouse

In mice and humans, loss of myosin VI (Myo6) function results in deafness, and certain Myo6 mutations also result in cardiomyopathies in humans. The current studies have utilized the Snell’s waltzer (sv) mouse (a functional null mutation for Myo6) to determine if this mouse also exhibits cardiac def...

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Detalhes bibliográficos
Publicado no:Cytoskeleton (Hoboken)
Main Authors: Hegan, Peter S., Lanahan, Anthony A., Simons, Michael, Mooseker, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600664/
https://ncbi.nlm.nih.gov/pubmed/26265212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21236
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