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Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

Idiopathic pulmonary fibrosis (IPF) is an age-related fatal disease with unknown etiology and no effective treatment. In this study, we show that primary cultures of fibroblasts derived from lung biopsies of IPF patients exhibited (i) accelerated replicative cellular senescence (CS); (ii) high resis...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Aging (Albany NY)
Päätekijät: Yanai, Hagai, Shteinberg, Albert, Porat, Ziv, Budovsky, Arie, Braiman, Alex, Zeische, Rolf, Fraifeld, Vadim E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600624/
https://ncbi.nlm.nih.gov/pubmed/26399448
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