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Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients

Idiopathic pulmonary fibrosis (IPF) is an age-related fatal disease with unknown etiology and no effective treatment. In this study, we show that primary cultures of fibroblasts derived from lung biopsies of IPF patients exhibited (i) accelerated replicative cellular senescence (CS); (ii) high resis...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yanai, Hagai, Shteinberg, Albert, Porat, Ziv, Budovsky, Arie, Braiman, Alex, Zeische, Rolf, Fraifeld, Vadim E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600624/
https://ncbi.nlm.nih.gov/pubmed/26399448
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