Effects of decreased lactate accumulation after dichloroacetate administration on exercise training–induced mitochondrial adaptations in mouse skeletal muscle

Recent studies suggested that lactate accumulation can be a signal for mitochondrial biogenesis in skeletal muscle. We investigated whether reductions in lactate concentrations in response to dichloroacetate (DCA), an activator of pyruvate dehydrogenase, attenuate mitochondrial adaptations after exe...

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Detaylı Bibliyografya
Yayımlandı:Physiol Rep
Asıl Yazarlar: Hoshino, Daisuke, Tamura, Yuki, Masuda, Hiroyuki, Matsunaga, Yutaka, Hatta, Hideo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Ltd 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600395/
https://ncbi.nlm.nih.gov/pubmed/26416973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12555
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