Down-regulation of USP13 mediates phenotype transformation of fibroblasts in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by fibroblastic foci and progressive scarring of the pulmonary parenchyma. IPF fibroblasts display increased proliferation and enhanced migration and invasion, analogous to cancer cells. This transformation-like phenoty...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Geng, Jing, Huang, Xiaoxi, Li, Ying, Xu, Xuefeng, Li, Shuhong, Jiang, Dingyuan, Liang, Jiurong, Jiang, Dianhua, Wang, Chen, Dai, Huaping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600336/
https://ncbi.nlm.nih.gov/pubmed/26453058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0286-3
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