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A protease storm cleaves a cell-cell adhesion molecule in cancer: multiple proteases converge to regulate PTPmu in glioma cells

Cleavage of the cell-cell adhesion molecule, PTPμ, occurs in human glioblastoma multiforme brain tumor tissue and glioma cell lines. PTPμ cleavage is linked to increased cell motility and growth factor independent survival of glioma cells in vitro. Previously, PTPμ was shown to be cleaved by furin i...

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Détails bibliographiques
Publié dans:J Cell Biochem
Auteurs principaux: Phillips-Mason, Polly J., Craig, Sonya E.L., Brady-Kalnay, Susann M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600327/
https://ncbi.nlm.nih.gov/pubmed/24771611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24824
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