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A protease storm cleaves a cell-cell adhesion molecule in cancer: multiple proteases converge to regulate PTPmu in glioma cells

Cleavage of the cell-cell adhesion molecule, PTPμ, occurs in human glioblastoma multiforme brain tumor tissue and glioma cell lines. PTPμ cleavage is linked to increased cell motility and growth factor independent survival of glioma cells in vitro. Previously, PTPμ was shown to be cleaved by furin i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cell Biochem
Prif Awduron: Phillips-Mason, Polly J., Craig, Sonya E.L., Brady-Kalnay, Susann M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600327/
https://ncbi.nlm.nih.gov/pubmed/24771611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24824
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