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A protease storm cleaves a cell-cell adhesion molecule in cancer: multiple proteases converge to regulate PTPmu in glioma cells

Cleavage of the cell-cell adhesion molecule, PTPμ, occurs in human glioblastoma multiforme brain tumor tissue and glioma cell lines. PTPμ cleavage is linked to increased cell motility and growth factor independent survival of glioma cells in vitro. Previously, PTPμ was shown to be cleaved by furin i...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Phillips-Mason, Polly J., Craig, Sonya E.L., Brady-Kalnay, Susann M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600327/
https://ncbi.nlm.nih.gov/pubmed/24771611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24824
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