Nortriptyline in knee osteoarthritis (NortIKA Study): study protocol for a randomised controlled trial

BACKGROUND: Osteoarthritis (OA) is a common cause of pain and disability. Currently available analgesics are often insufficiently effective or have unacceptable adverse effects. Tricyclic antidepressants may offer a useful centrally-acting analgesic. Nortriptyline is a readily-available, cheap and c...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Hudson, Ben, Williman, Jonathan A., Stamp, Lisa K., Alchin, John S., Hooper, Gary J., Mangin, Dee, Thompson, Bronwyn F., Toop, Les
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600280/
https://ncbi.nlm.nih.gov/pubmed/26453560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-015-0961-1
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