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Strain-Promoted Reaction of 1,2,4-Triazines with Bicyclononynes
Strain-promoted inverse electron-demand Diels–Alder cycloaddition (SPIEDAC) reactions between 1,2,4,5-tetrazines and strained dienophiles, such as bicyclononynes, are among the fastest bioorthogonal reactions. However, the synthesis of 1,2,4,5-tetrazines is complex and can involve volatile reagents....
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| Publicado en: | Chemistry |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
WILEY-VCH Verlag
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4600244/ https://ncbi.nlm.nih.gov/pubmed/26275391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201502397 |
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