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Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection

With over 3.5 billion people at risk and approximately 390 million human infections per year, dengue virus (DENV) disease strains health care resources worldwide. Previously, we and others established models for DENV pathogenesis in mice that completely lack subunits of the receptors (Ifnar and Ifng...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Pinto, Amelia K., Brien, James D., Lam, Chia-Ying Kao, Johnson, Syd, Chiang, Cindy, Hiscott, John, Sarathy, Vanessa V., Barrett, Alan D., Shresta, Sujan, Diamond, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600115/
https://ncbi.nlm.nih.gov/pubmed/26374123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01316-15
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