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Different somatic mutations in multinodular adrenals with aldosterone producing adenoma

Primary aldosteronism is the most common form of secondary hypertension. Somatic mutations in KCNJ5, ATP1A1, ATP2B3 and CACNA1D are found in aldosterone producing adenoma. Additionally, adrenals with aldosterone producing adenomas show cortical remodeling and frequently multiple secondary nodules. O...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Fernandes-Rosa, Fabio Luiz, Giscos-Duriez, Isabelle, Amar, Laurence, Gomez-Sanchez, Celso E., Meatchi, Tchao, Boulkroun, Sheerazed, Zennaro, Maria-Christina
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600038/
https://ncbi.nlm.nih.gov/pubmed/26351028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05993
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