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Organosilane and Polyethylene Glycol Functionalized Magnetic Mesoporous Silica Nanoparticles as Carriers for CpG Immunotherapy In Vitro and In Vivo

Cytosine–guanine (CpG) containing oligodeoxynucleotides (ODN) have significant clinical potential as immunotherapeutics. However, limitations exist due to their transient biological stability in vivo, lack of specificity for target cells, and poor cellular uptake. To address these issues, we prepare...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Zheng, Hengrui, Wen, Songsong, Zhang, Yang, Sun, Zhenliang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599948/
https://ncbi.nlm.nih.gov/pubmed/26451735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140265
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