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Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and Gastrin

One week of treatment with EGF and gastrin (EGF/G) was shown to restore normoglycemia and to induce islet regeneration in mice treated with the diabetogenic agent alloxan. The mechanisms underlying this regeneration are not fully understood. We performed genetic lineage tracing experiments to evalua...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Song, Imane, Patel, Oelfah, Himpe, Eddy, Muller, Christo J. F., Bouwens, Luc
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599944/
https://ncbi.nlm.nih.gov/pubmed/26452142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140148
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