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HuR and Ago2 Bind the Internal Ribosome Entry Site of Enterovirus 71 and Promote Virus Translation and Replication

EV71 (enterovirus 71) RNA contains an internal ribosomal entry site (IRES) that directs cap-independent initiation of translation. IRES-dependent translation requires the host’s translation initiation factors and IRES-associated trans-acting factors (ITAFs). We reported recently that mRNA decay fact...

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Bibliographic Details
Published in:PLoS One
Main Authors: Lin, Jing-Yi, Brewer, Gary, Li, Mei-Ling
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599798/
https://ncbi.nlm.nih.gov/pubmed/26451954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140291
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