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Ideal sphere-forming culture conditions to maintain pluripotency in a hepatocellular carcinoma cell lines

BACKGROUND: Cancer stem cells (CSCs) constitute 1–2 % of cancer tissue and are a major cause of tumor metastasis and recurrence. The culture environment is important in maintaining CSCs in vitro. Sphere formation is one method of culturing CSCs. In this study, we identified and validated optimal cul...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Min, Seon Ok, Lee, Sang Woo, Bak, Seon Young, Kim, Kyung Sik
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599746/
https://ncbi.nlm.nih.gov/pubmed/26457068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0240-y
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