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Molecular Mechanisms Regulating Impaired Neurogenesis of Fragile X Syndrome Human Embryonic Stem Cells

Fragile X syndrome (FXS) is the most common form of inherited cognitive impairment. It is caused by developmental inactivation of the FMR1 gene and the absence of its encoded protein FMRP, which plays pivotal roles in brain development and function. In FXS embryos with full FMR1 mutation, FMRP is ex...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Stem Cells Dev
मुख्य लेखकों: Telias, Michael, Mayshar, Yoav, Amit, Ami, Ben-Yosef, Dalit
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Mary Ann Liebert, Inc. 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599386/
https://ncbi.nlm.nih.gov/pubmed/26393806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0220
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