Activin-receptor signaling regulates cocaine-primed behavioral and morphological plasticity

Cocaine addiction is a life-long relapsing disorder that results from long-term adaptations within the brain. We find that Activin-receptor signaling, including the transcription factor Smad3, is upregulated in the rat nucleus accumbens shell following withdrawal from cocaine. Direct genetic and pha...

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Bibliographic Details
Published in:Nat Neurosci
Main Authors: Gancarz, Amy M., Wang, Zi-Jun, Schroeder, Gabrielle L., Damez-Werno, Diane, Braunscheidel, Kevin, Mueller, Lauren E., Humby, Monica S., Caccamise, Aaron, Martin, Jennifer A., Dietz, Karen C., Neve, Rachael L., Dietz, David M.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599345/
https://ncbi.nlm.nih.gov/pubmed/26030849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4036
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