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Instability in progressive multiple sequence alignment algorithms

BACKGROUND: Progressive alignment is the standard approach used to align large numbers of sequences. As with all heuristics, this involves a tradeoff between alignment accuracy and computation time. RESULTS: We examine this tradeoff and find that, because of a loss of information in the early steps...

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Detalhes bibliográficos
Publicado no:Algorithms Mol Biol
Main Authors: Boyce, Kieran, Sievers, Fabian, Higgins, Desmond G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599319/
https://ncbi.nlm.nih.gov/pubmed/26457114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-015-0057-1
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