High-throughput RNAi screening of human kinases identifies predictors of clinical outcome in colorectal cancer patients treated with oxaliplatin

The purpose of this study is to identify protein kinase genes that modulate oxaliplatin cytotoxicity in vitro and evaluate the roles of these genes in predicting clinical outcomes in CRC patients receiving oxaliplatin-based adjuvant chemotherapy. A high-throughput RNAi screening targeting 626 human...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Lin, Moubin, Zhang, Yajie, Li, Ajian, Tang, Erjiang, Peng, Jian, Tang, Wenxian, Zhang, Yong, Lu, Liang, Xiao, Yihua, Wei, Qing, Yin, Lu, Li, Huaguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Clinical Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599307/
https://ncbi.nlm.nih.gov/pubmed/25904054
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