Deguelin inhibits vasculogenic function of endothelial progenitor cells in tumor progression and metastasis via suppression of focal adhesion

Deguelin is a nature-derived chemopreventive drug. Endothelial progenitor cells (EPCs) are bone-marrow (BM)-derived key components to induce new blood vessels in early tumorigenesis and metastasis. Here we determined whether deguelin inhibits EPC function in vitro and in vivo at doses not affecting...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Nguyen, Minh Phuong, Lee, Dongjin, Lee, Se-Hyung, Lee, Hye-Eun, Lee, Ho-Young, Lee, You Mie
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599291/
https://ncbi.nlm.nih.gov/pubmed/26078334
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