Accumulation of ALDH1-positive cells after neoadjuvant chemotherapy predicts treatment resistance and prognosticates poor outcome in ovarian cancer

Although ovarian cancer is a highly chemosensitive disease, it is only infrequently cured. One of the major reasons lies in the presence of drug-resistant cancer stem-like cells, sufficient to fuel recurrence. We phenotyped cancer stem-like cells by flow cytometry and immunohistochemistry in 55 matc...

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Udgivet i:Oncotarget
Main Authors: Ayub, Tiyasha H., Keyver-Paik, Mignon-Denise, Debald, Manuel, Rostamzadeh, Babak, Thiesler, Thore, Schröder, Lars, Barchet, Winfried, Abramian, Alina, Kaiser, Christina, Kristiansen, Glen, Kuhn, Walther, Kübler, Kirsten
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599280/
https://ncbi.nlm.nih.gov/pubmed/25999351
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