Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner

Obesity greatly influences risk, progression and prognosis of breast cancer. As molecular effects of obesity are largely mediated by adipocytokine leptin, finding effective novel strategies to antagonize neoplastic effects of leptin is desirable to disrupt obesity-cancer axis. Present study is desig...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Avtanski, Dimiter B., Nagalingam, Arumugam, Kuppusamy, Panjamurthy, Bonner, Michael Y., Arbiser, Jack L., Saxena, Neeraj K., Sharma, Dipali
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599277/
https://ncbi.nlm.nih.gov/pubmed/26036628
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