Leptin signaling enhances cell invasion and promotes the metastasis of human pancreatic cancer via increasing MMP-13 production

Emerging evidence has suggested that leptin, an adipokine related to energy homeostasis, plays a role in cancer growth and metastasis. However, its impact on pancreatic cancer is rarely studied. In this study, we found that leptin's functional receptor Ob-Rb was expressed in pancreatic cancer c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fan, Yingchao, Gan, Yu, Shen, Yuling, Cai, Xiaojin, Song, Yanfang, Zhao, Fangyu, Yao, Ming, Gu, Jianren, Tu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599260/
https://ncbi.nlm.nih.gov/pubmed/25948792
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