Chargement en cours...

Restoration of CCAAT enhancer binding protein α P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells

All-trans retinoic acid (ATRA) is one of the first line agents in differentiation therapy for acute promyelocytic leukemia (APL). However, drug resistance is a major problem influencing the efficacy of ATRA. Identification of mechanisms of ATRA resistance are urgenly needed. In the present study, we...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Int J Oncol
Auteurs principaux: WANG, LIMENGMENG, XIAO, HAOWEN, ZHANG, XING, LIAO, WEICHAO, FU, SHAN, HUANG, HE
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599186/
https://ncbi.nlm.nih.gov/pubmed/26397153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3163
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!