Inflammation decreases keratin level in ulcerative colitis; inadequate restoration associates with increased risk of colitis-associated cancer

BACKGROUND: Keratins are intermediate filament (IF) proteins, which form part of the epithelial cytoskeleton and which have been implicated pathology of inflammatory bowel diseases (IBD). METHODS: In this study biopsies were obtained from IBD patients grouped by disease duration and subtype into eig...

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Detalhes bibliográficos
Publicado no:BMJ Open Gastroenterol
Main Authors: Corfe, Bernard M, Majumdar, Debabrata, Assadsangabi, Arash, Marsh, Alexandra M R, Cross, Simon S, Connolly, Joanne B, Evans, Caroline A, Lobo, Alan J
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Inflammatory Bowel Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599170/
https://ncbi.nlm.nih.gov/pubmed/26462276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjgast-2014-000024
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