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Genome-wide Mechanosensitive MicroRNA (MechanomiR) Screen Uncovers Dysregulation of Their Regulatory Networks in the mdm Mouse Model of Muscular Dystrophy

Muscular dystrophies (MDs) are a heterogeneous group of genetic and neuromuscular disorders, which result in severe loss of motor ability and skeletal muscle mass and function. Aberrant mechanotransduction and dysregulated-microRNA pathways are often associated with the progression of MD. Here, we h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Mohamed, Junaith S., Hajira, Ameena, Lopez, Michael A., Boriek, Aladin M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599005/
https://ncbi.nlm.nih.gov/pubmed/26272747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.659375
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