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Prerequisites for Functional Interleukin 31 Signaling and Its Feedback Regulation by Suppressor of Cytokine Signaling 3 (SOCS3)

Interleukin-31 (IL-31) is a T helper type 2 cell-derived cytokine tightly associated with inflammatory skin disorders. IL-31-induced signaling is mediated by a receptor complex composed of oncostatin M receptor β and the cytokine-specific receptor subunit IL-31Rα, of which there are several isoforms...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Maier, Elisabeth, Mittermeir, Michaela, Ess, Stefanie, Neuper, Theresa, Schmiedlechner, Angela, Duschl, Albert, Horejs-Hoeck, Jutta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598987/
https://ncbi.nlm.nih.gov/pubmed/26306032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661306
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