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HOXA4 Provides Stronger Engraftment Potential to Short-Term Repopulating Cells Than HOXB4

Genes of the HOX4 paralog group have been shown to expand hematopoietic stem cells (HSCs). Endogenous expression of HOXA4 is 10-fold higher than HOXB4 in embryonic primitive hematopoietic cells undergoing self-renewal suggesting a more potent capacity of HOXA4 to expand HSC. In this study, we provid...

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Detalles Bibliográficos
Publicado en:Stem Cells Dev
Autores principales: Fournier, Marilaine, Lebert-Ghali, Charles-Étienne, Bijl, Janetta J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598939/
https://ncbi.nlm.nih.gov/pubmed/26166023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0063
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