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Predominant role of interferon-γ in the host protective effect of CD8(+) T cells against Neospora caninum infection

It is well established that CD8(+) T cells play an important role in protective immunity against protozoan infections. However, their role in the course of Neospora caninum infection has not been fully elucidated. Here we report that CD8-deficient mice infected with N. caninum presented higher paras...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Correia, Alexandra, Ferreirinha, Pedro, Botelho, Sofia, Belinha, Ana, Leitão, Catarina, Caramalho, Íris, Teixeira, Luzia, González-Fernandéz, África, Appelberg, Rui, Vilanova, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598874/
https://ncbi.nlm.nih.gov/pubmed/26449650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14913
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