Identification of cellular microRNA-136 as a dual regulator of RIG-I-mediated innate immunity that antagonizes H5N1 IAV replication in A549 cells

H5N1 influenza A virus (IAV) causes severe respiratory diseases and high mortality rates in animals and humans. MicroRNAs are being increasingly studied to evaluate their potential as therapeutic entities to combat viral infection. However, mechanistic studies delineating the roles of microRNAs in r...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Zhao, Lianzhong, Zhu, Jiping, Zhou, Hongbo, Zhao, Zongzheng, Zou, Zhong, Liu, Xiaokun, Lin, Xian, Zhang, Xue, Deng, Xuexia, Wang, Ruifang, Chen, Huanchun, Jin, Meilin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598873/
https://ncbi.nlm.nih.gov/pubmed/26450567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14991
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