CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis

The complement system is important for the host defence against infection as well as for the development of inflammatory diseases. Here we show that C1q/TNF-related protein 6 (CTRP6; gene symbol C1qtnf6) expression is elevated in mouse rheumatoid arthritis (RA) models. C1qtnf6(−/−) mice are highly s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Murayama, Masanori A., Kakuta, Shigeru, Inoue, Asuka, Umeda, Naoto, Yonezawa, Tomo, Maruhashi, Takumi, Tateishi, Koichiro, Ishigame, Harumichi, Yabe, Rikio, Ikeda, Satoshi, Seno, Akimasa, Chi, Hsi-Hua, Hashiguchi, Yuriko, Kurata, Riho, Tada, Takuya, Kubo, Sachiko, Sato, Nozomi, Liu, Yang, Hattori, Masahira, Saijo, Shinobu, Matsushita, Misao, Fujita, Teizo, Sumida, Takayuki, Iwakura, Yoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598845/
https://ncbi.nlm.nih.gov/pubmed/26404464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9483
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