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Exchanging ligand-binding specificity between a pair of mouse olfactory receptor paralogs reveals odorant recognition principles

A multi-gene family of ~1000 G protein-coupled olfactory receptors (ORs) constitutes the molecular basis of mammalian olfaction. Due to the lack of structural data its remarkable capacity to detect and discriminate thousands of odorants remains poorly understood on the structural level of the recept...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Baud, Olivia, Yuan, Shuguang, Veya, Luc, Filipek, Slawomir, Vogel, Horst, Pick, Horst
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598832/
https://ncbi.nlm.nih.gov/pubmed/26449412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14948
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