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Lower glycolysis carries a higher flux than any biochemically possible alternative

The universality of many pathways of core metabolism suggests a strong role for evolutionary selection, but it remains unclear whether existing pathways have been selected from a large or small set of biochemical possibilities. To address this question, we construct in silico all possible biochemica...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Court, Steven J., Waclaw, Bartlomiej, Allen, Rosalind J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598745/
https://ncbi.nlm.nih.gov/pubmed/26416228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9427
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