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CPI motif interaction is necessary for capping protein function in cells

Capping protein (CP) has critical roles in actin assembly in vivo and in vitro. CP binds with high affinity to the barbed end of actin filaments, blocking the addition and loss of actin subunits. Heretofore, models for actin assembly in cells generally assumed that CP is constitutively active, diffu...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Edwards, Marc, McConnell, Patrick, Schafer, Dorothy A., Cooper, John A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598739/
https://ncbi.nlm.nih.gov/pubmed/26412145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9415
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